The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2026

Filed:

Aug. 20, 2019
Applicants:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Industry-university Cooperation Foundation Hanyang University, Seoul, KR;

Inventors:

Dong-Pyo Jang, Sungnam City, KR;

Kendall H. Lee, Rochester, MN (US);

Yoonbae Oh, Rochester, MN (US);

Christopher J. Kimble, Pine Island, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); G01N 27/327 (2006.01); G01N 33/487 (2006.01); A61B 5/1473 (2006.01);
U.S. Cl.
CPC ...
A61B 5/14546 (2013.01); G01N 27/3277 (2013.01); G01N 33/48707 (2013.01); A61B 5/1473 (2013.01);
Abstract

Systems, methods, and devices for generating multiple cyclic square-waveforms and sloped-edge square waveforms. Aspects of the techniques disclosed herein include applying the generated waveforms to an electrode used in voltammetry, e.g., to measure a level of a neurochemical in neural tissue. An electrode can be located in a solution, and an electrical stimulus applied to the solution through the electrode using a multiple cyclic square waveform. An electrical current response to the stimulus is measured, and a level of an analyte (e.g., dopamine or other neurochemical(s)) determined based on the electrical current response.


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