The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2026

Filed:

Feb. 27, 2024
Applicant:

Electronics and Telecommunications Research Institute, Daejeon, KR;

Inventors:

Sang Kyun Lee, Daejeon, KR;

Dong Hoon Song, Daejeon, KR;

Chul Huh, Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 3/13 (2006.01); A61B 3/12 (2006.01); B06B 1/06 (2006.01); G02B 21/00 (2006.01);
U.S. Cl.
CPC ...
A61B 3/13 (2013.01); A61B 3/1225 (2013.01); B06B 1/067 (2013.01); G02B 21/0012 (2013.01); B06B 2201/76 (2013.01);
Abstract

The present invention proposes a technology that enables in vivo imaging while expanding the penetration depth of light into the tissue in an ultrasound-induced optical clearing microscopy (USOCM) system using an optical microscope, in particular, a non-linear optical microscope such as a two-photon microscope, and an ultrasonic transducer. For maximum efficiency, the ultrasonic transducer should be positioned between an optical microscope (objective lens) and the sample. In this case, since an existing ultrasonic transducer is opaque, a laser beam of an optical microscope using an ultrashort laser system cannot pass through the existing ultrasonic transducer. In order to solve such a problem, a transparent ultrasonic transducer is applied such that there is no problem in a laser beam passing therethrough and reaching a sample.


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