The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2026

Filed:

Apr. 27, 2022
Applicant:

Suzhou Boundless Medical Technology Co., Ltd., Suzhou, CN;

Inventors:

Yu Sun, Toronto, CA;

Guanqiao Shan, Toronto, CA;

Changsheng Dai, Toronto, CA;

Zhuoran Zhang, Toronto, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/1429 (2024.01); G01N 15/1434 (2024.01); G02B 21/36 (2006.01); G02B 30/54 (2020.01);
U.S. Cl.
CPC ...
G02B 21/367 (2013.01); G01N 15/1429 (2013.01); G02B 30/54 (2020.01); G01N 2015/1445 (2013.01);
Abstract

Systems and methods for detecting and 3D imaging of cell junctions on a cell layer of a biological structure, such as a blastocyst, are provided. The method can include operating a microscope to view a portion of the biological structure; rotating the biological structure through a set of orientations; capturing, at each orientation, a respective image of a corresponding one of a set of cell layer regions of the cell layer, wherein each cell layer region partly overlaps with at least another cell layer region, thereby obtaining a set of partially overlapping cell layer images; creating a cell layer texture map containing cell junction information from the set of cell layer images; and constructing a 3D image of the cell junctions based on the cell layer texture map and the cell junction information contained therein.


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