The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2026

Filed:

Apr. 28, 2022
Applicant:

University of Central Florida Research Foundation, Inc., Orlando, FL (US);

Inventors:

Debashis Chanda, Oviedo, FL (US);

Abraham Vazquez-Guardado, Evanston, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B01L 3/00 (2006.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
G01N 33/54373 (2013.01); B01L 3/502715 (2013.01); B01L 3/502753 (2013.01); B01L 3/502761 (2013.01); B01L 2300/0877 (2013.01); C12N 15/115 (2013.01); G01N 2333/185 (2013.01);
Abstract

A method is for detecting a biomarker within a sample of blood. The method may include processing the sample of blood with a microfluidic blood plasma separator and a plasmonic array biosensor, and flowing the sample of blood over a sensing surface of the plasmonic array biosensor. The sensing surface of the plasmonic array biosensor may have an ssDNA aptamer against the biomarker. The method may further include binding the biomarker in the sample of blood to the ssDNA aptamer of the plasmonic array biosensor, and detecting the biomarker in the sample of blood based upon LSPR altering a reflected optical signal from the plasmonic array biosensor.


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