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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12735444 B1

PDFFull Text
Date of Patent:
Sep. 15, 2026

Filed:

Sep. 16, 2020

Chemically cleavable group

Applicant:

Tagworks Pharmaceuticals B.v., Eindhoven, NL;

Inventors:

Marc Stefan Robillard, Eindhoven, NL;

Ronny Mathieu Versteegen, Eindhoven, NL;

Wolter Ten Hoeve, Eindhoven, NL;

Raffaella Rossin, Eindhoven, NL;

Assignee:

Tagworks Pharmaceuticals B.V., Nijmegen, NL;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Ana Z Muresan

Int. Cl.
CPC ...
C07C 209/62 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); A61K 47/68 (2017.01); B82Y 5/00 (2011.01); C07C 29/10 (2006.01); C07C 37/50 (2006.01); C07C 45/61 (2006.01); C07C 205/20 (2006.01); C07C 205/57 (2006.01); C07H 15/252 (2006.01); G01N 33/543 (2006.01); G01N 33/60 (2006.01);
U.S. Cl.
CPC ...
C07H 15/252 (2013.01); A61K 47/555 (2017.08); A61K 47/60 (2017.08); A61K 47/6897 (2017.08); B82Y 5/00 (2013.01); C07C 29/10 (2013.01); C07C 37/50 (2013.01); C07C 45/61 (2013.01); C07C 205/20 (2013.01); C07C 205/57 (2013.01); C07C 209/62 (2013.01); G01N 33/54353 (2013.01); G01N 33/60 (2013.01);
Abstract

Disclosed is the use of the reactive components of the inverse electron-demand Diels Alder reaction for chemical masking and unmasking in vitro. This can be applied in complex chemical reactions and, particularly in the synthesis of biomolecules, e.g. on solid supports. The reactice components are a dienophile, particularly a trans-cyclooctene, and a diene, particularly a tetrazine.

Find Patent Forward Citations

Robillard, Marc. (2026). Chemically cleavable group (U.S. Patent No. 12735444). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12735444

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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