The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2026
Filed:
May. 15, 2023
Applicant:
Enliven Inc., Burlingame, CA (US);
Inventors:
Joseph P. Lyssikatos, Boulder, CO (US);
Samuel Kintz, Boulder, CO (US);
Li Ren, Superior, CO (US);
Qiang Su, Beijing, CN;
Assignee:
Enliven Inc., Burlingame, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/18 (2006.01); A61P 35/02 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/18 (2013.01); A61P 35/02 (2018.01); C07D 519/00 (2013.01); C07B 2200/05 (2013.01);
Abstract
The present disclosure relates generally to compounds and compositions thereof for inhibition of ErbB2, including mutant forms of ErbB2, particularly those harboring an Exon 20 mutation, methods of preparing said compounds and compositions, and their use in the treatment or prophylaxis of various cancers, such as lung, glioma, skin, head neck, salivary gland, breast, esophageal, liver, stomach (gastric), uterine, cervical, biliary tract, pancreatic, colorectal, renal, bladder or prostate cancer.