The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2026
Filed:
Mar. 07, 2022
Applicant:
Research Triangle Institute, Research Triangle Park, NC (US);
Inventors:
Chunyang Jin, Apex, NC (US);
Elaine Gay, Chapel Hill, NC (US);
Assignee:
RESEARCH TRIANGLE INSTITUTE, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61K 31/4245 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/4245 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01); C07D 413/12 (2013.01);
Abstract
Non-peptide, small molecule antagonists of the relaxin family peptide 3 receptor (RXPP3) that can inhibit relaxin-3 activity are described. The compounds can include a pyrrolidone or piperidone substituted with an aryl amide. Also described are methods of preparing the antagonists and methods of using the antagonists to treat diseases, disorders and conditions, such as obesity, alcoholism and other substance abuse and/or addiction-related conditions.