The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2026

Filed:

Feb. 03, 2020
Applicant:

Genzyme Corporation, Cambridge, MA (US);

Inventors:

Nigel Patrick Somerville Crawford, Califon, NJ (US);

Tanya Zaremba Fischer, Newton, MA (US);

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/439 (2006.01); A61K 38/47 (2006.01); A61P 3/00 (2006.01); A61P 17/00 (2006.01); A61P 25/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/439 (2013.01); A61K 38/47 (2013.01); A61P 3/00 (2018.01); A61P 17/00 (2018.01); A61P 25/02 (2018.01); C12Y 302/01045 (2013.01);
Abstract

This disclosure to methods for treating or preventing particular symptoms and disorders which are associated with lysosomal storage diseases using quinuclidine compounds of formula (I), optionally in combination with enzyme replacement therapy. This includes pain, such as abdominal pain, and dermatological disorders, such as angiokeratoma, in a patient having a disease such as Fabry disease. Also disclosed is a pharmaceutical composition comprising a quinuclidine compound for use in said methods.


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