The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2026
Filed:
Feb. 27, 2023
Thornhill Scientific Inc., North York, CA;
James Duffin, Toronto, CA;
Joseph Arnold Fisher, Thornhill, CA;
David Mikulis, Oakville, CA;
Ece Su Sayin, Windsor, CA;
Jacob B. Schulman, Toronto, CA;
Olivia Sobczyk, Etobicoke, CA;
Kamil Uludag, Toronto, CA;
THORNHILL SCIENTIFIC INC., North York, CA;
Abstract
Hypoxia-induced deoxyhemoglobin concentration ([dOHb]) may be used as a susceptibility contrast agent in subjects. With sequential gas delivery methods, reoxygenation can be implemented abruptly, inducing an arterial input function with a square shape. Since the concentration of deoxyhemoglobin is known, the arterial input function can be pre-determined and perfusion metrics can be completed without error-prone measurements. Pre-determined arterial input functions provide a faster, more reliable method of analyzing BOLD-MRI images, and the resolution is not limited by the breath rate.