The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

May. 20, 2021
Applicant:

Dh Technologies Development Pte. Ltd., Singapore, SG;

Inventors:

Thomas R. Covey, Concord, CA;

Chang Liu, Concord, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 27/624 (2021.01); G01N 27/74 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6851 (2013.01); G01N 27/624 (2013.01); G01N 27/745 (2013.01); G01N 33/54326 (2013.01);
Abstract

In a system for affinity selection by mass spectrometry, wherein a plurality of drug candidates in solution are separated based on affinity, a method is provided comprising introducing a solid-phase device having binding affinity for a selected protein into the solution, binding at least one of the plurality of drug candidates to the solid-phase device as a selected drug candidate, washing the solid-phase device and selected drug candidate to separate unbound material, sampling the selected drug candidate in capture fluid flowing through a sampling region of an open port sampling interface and directing the sampled selected drug candidate and capture fluid to an ionization source.


Find Patent Forward Citations

Loading…