The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

Apr. 16, 2023
Applicant:

Shanghai Ruiyu Biotech. Co., Ltd., Shanghai, CN;

Inventors:

Puwen Luo, Shanghai, CN;

Jing Jiang, Shanghai, CN;

Kai Chen, Shanghai, CN;

Weiya Fan, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06T 7/136 (2017.01); G06T 7/33 (2017.01); G06T 7/90 (2017.01);
U.S. Cl.
CPC ...
G01N 33/5047 (2013.01); G01N 33/5011 (2013.01); G06T 7/0014 (2013.01); G06T 7/11 (2017.01); G06T 7/136 (2017.01); G06T 7/33 (2017.01); G06T 7/90 (2017.01); G01N 2500/10 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/20221 (2013.01); G06T 2207/30024 (2013.01);
Abstract

The embodiments of the present disclosure provide a method, a system, and an application for detecting at least one of a cell-killing efficacy or an immune activity. The method comprises: obtaining a plurality of microscopic images of a fixed area of a co-culture sample, wherein the co-culture sample is a cell sample obtained by co-culturing target cells and effector cells, the fixed area of the co-culture sample includes a plurality of objects, wherein the plurality of objects are a cell group including cells with different properties, each of the plurality of objects having an image-identifiable feature; performing an image overlapping synthesis analysis or an image fusion analysis for the plurality of microscopic images to obtain the cell properties of the plurality of objects and make statistics to cell parameters associated with the cell properties; and evaluating at least one of the cell-killing efficacy or the immune activity of the effector cells based on the cell parameters.


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