The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2026
Filed:
May. 10, 2024
Applicant:
Ion Dx, Inc., Monterey, CA (US);
Inventors:
W. Henry Benner, Carmel, CA (US);
Ben Aguilar, Monterey, CA (US);
Assignee:
ION DX, INC., Monterey, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/42 (2006.01);
U.S. Cl.
CPC ...
G01N 1/42 (2013.01);
Abstract
Apparatus and methods are described for preparing samples for examination by cryo-electron microscopy. Molecules of interest, such as protein molecules in a solution, are electrosprayed and converted to singly-charged gas-phase ions. Particular conformation(s) of the protein ions are selected by using an ion mobility filter and deposited onto a cryo-EM grid at sub-eV kinetic energy for the purpose of preserving the molecule's higher order structure.