The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

Sep. 02, 2025
Applicants:

Immunedge, Inc., Redwood City, CA (US);

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Bo Yu, Mountain View, CA (US);

Edgar G. Engleman, Atherton, CA (US);

Xiangyue Zhang, Sunnyvale, CA (US);

David Kung-Chun Chiu, Mountain View, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 37/02 (2006.01); A61P 37/06 (2006.01); C07K 14/505 (2006.01); C07K 16/22 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A61P 37/02 (2018.01); A61P 37/06 (2018.01); C07K 14/505 (2013.01); C07K 16/22 (2013.01); C12N 15/113 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/70 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01); C12N 2310/14 (2013.01);
Abstract

The present disclosure provides anti-EPOR antibodies, anti-EPO antibodies, and fragments thereof that specifically bind to the hetero-EPOR or homo-EPOR or EPO with high affinity. The anti-EPOR antibodies, anti-EPO antibodies, and/or engineered EPOs can be used to treat patients.


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