The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

Dec. 16, 2021
Applicant:

Astrazeneca Ab, Södertälje, SE;

Inventors:

Jonas Brånalt, Gothenberg, SE;

Björn Holm, Gothenberg, SE;

Maria Johansson, Gothenberg, SE;

Olle Karlsson, Gothenberg, SE;

Daniel Laurent Knerr, Gothenberg, SE;

Anneli Nordqvist, Gothenberg, SE;

Robert John Sheppard, Gothenberg, SE;

Marianne Swanson, Gothenberg, SE;

Anna Tomberg, Gothenberg, SE;

Assignee:

AstraZeneca AB, Södertälje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); A61P 1/16 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 487/10 (2006.01); C07D 491/107 (2006.01); C07D 491/113 (2006.01); C07D 493/10 (2006.01); C07D 495/10 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61P 1/16 (2018.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C07D 491/107 (2013.01); C07D 491/113 (2013.01); C07D 493/10 (2013.01); C07D 495/10 (2013.01); C07D 498/08 (2013.01);
Abstract

Compounds having the structure of Formula (I): and pharmaceutically acceptable salts thereof, wherein X, R, R, R, R, Rand Rare as defined in the specification; pharmaceutical compositions comprising such compounds and salts; use of such compounds and salts to treat or prevent Prolyl endopeptidase fibroblast activation protein (FAP)-mediated conditions; kits comprising such compounds and salts; and methods for manufacturing such compounds and salts.


Find Patent Forward Citations

Loading…