The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2026
Filed:
Dec. 14, 2022
Celgene Quanticel Research, Inc., San Diego, CA (US);
John Fitzgerald Traverse, Summit, NJ (US);
Kelvin Hin-Yeong Yong, Summit, NJ (US);
Antonio Christian Ferretti, Summit, NJ (US);
Hekla Alite, Carteret, NJ (US);
Jonathan Moseley, Bristol, GB;
Antonio Maria Ruda, Cardiff, GB;
David Primer, Summit, NJ (US);
Steven Philp, Abingdon, GB;
Celgene Quanticel Research, Inc., San Diego, CA (US);
Abstract
The present invention provides processes of synthesis and purification of a bromodomain inhibitor, Compound 1, which compound includes crystalline forms, amorphous forms, solvates, and hydrates thereof. Embodiments of the disclosure relate to chemical synthesis routes of Compound 1 that provide a scalable method that results in highly pure final product. A further embodiment relates to methods to isolate the most stable polymorph of Compound 1 by crystallization from formic acid and water.