The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

Apr. 17, 2023
Applicants:

Memorial Sloan-kettering Cancer Center, New York, NY (US);

Memorial Hospital for Cancer and Allied Diseases, New York, NY (US);

Sloan-kettering Institute for Cancer Research, New York, NY (US);

Inventors:

Antonio Damato, White Plains, NY (US);

Joel Beaudry, New York, NY (US);

Gil'ad Cohen, Tenafly, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61N 5/1001 (2013.01); A61N 5/1031 (2013.01);
Abstract

Systems and methods for HDR brachytherapy planning can include obtaining patient specific data of a patient, and determining, using the patient specific data, an optimization problem to solve for a single-fraction HDR monotherapy plan including an objective function to be optimized subject to one or more first constraints on radiation doses within one or more OAR regions and a second constraint on radiation doses within the PTV. The systems and methods can include optimizing the objective function subject to the one or more first constraints and the second constraint, determining whether the first single-fraction HDR monotherapy plan satisfies the first and second constraints, updating a bound value of the second constraint based on whether the first single-fraction HDR monotherapy plan satisfies the first and second constraints, and optimizing the objective function subject to the one or more first constraints and the second constraint with the updated bound value.


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