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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12728247 B1

PDFFull Text
Date of Patent:
Sep. 08, 2026

Filed:

Dec. 18, 2020

Microneedle device and method for producing same

Applicant:

Hisamitsu Pharmaceutical Co., Inc., Tosu, JP;

Inventors:

Tatsuya Shimizu, Tsukuba, JP;

Takako Esu, Tsukuba, JP;

Shinpei Nishimura, Tsukuba, JP;

Assignee:

HISAMITSU PHARMACEUTICAL CO., INC., Tosu, JP;

Attorneys:

Nath, Goldberg & Meyer

Joshua B. Goldberg

Primary Examiner:

Bethany P Barham

Assistant Examiner:

Alexandra Nicole Isnor

Int. Cl.
CPC ...
A61K 31/137 (2006.01); A61K 9/00 (2006.01); A61K 31/4174 (2006.01); A61K 47/18 (2017.01); A61K 47/36 (2006.01); A61L 31/08 (2006.01); A61L 31/16 (2006.01); A61M 37/00 (2006.01);
U.S. Cl.
CPC ...
A61M 37/0015 (2013.01); A61K 9/0021 (2013.01); A61K 31/137 (2013.01); A61K 31/4174 (2013.01); A61K 47/183 (2013.01); A61K 47/36 (2013.01); A61L 31/08 (2013.01); A61L 31/16 (2013.01); A61L 2420/02 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0046 (2013.01); A61M 2037/0053 (2013.01); A61M 2205/0238 (2013.01);
Abstract

The present invention aims to provide a method for producing a microneedle device comprising a coating comprising dexmedetomidine and isoproterenol, in which the stability of isoproterenol during production and after production of the microneedle device is high. A method for producing a microneedle device according to one embodiment of the present invention comprises coating microneedles with a coating liquid to form a coating on the microneedles. The microneedle device comprises a substrate, microneedles disposed on the substrate, and a coating formed on the microneedles. The coating liquid comprises dexmedetomidine or a pharmaceutically acceptable salt thereof, isoproterenol or a pharmaceutically acceptable salt thereof, ethylenediaminetetraacetic acid or a pharmaceutically acceptable salt thereof, and a sulfated polysaccharide.

Find Patent Forward Citations

Shimizu, Tatsuya. (2026). Microneedle device and method for producing same (U.S. Patent No. 12728247). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12728247

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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