The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

Jun. 08, 2023
Applicant:

Becton, Dickinson and Company, Franklin Lakes, NJ (US);

Inventors:

Christopher Quach, North Salt Lake, UT (US);

Dustin Payne, West Jordan, UT (US);

Assignee:

Becton, Dickinson and Company, Franklin Lakes, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 33/00 (2006.01); A61L 29/08 (2006.01); A61L 29/14 (2006.01); A61L 29/16 (2006.01); A61L 33/06 (2006.01); A61L 33/08 (2006.01);
U.S. Cl.
CPC ...
A61L 33/0064 (2013.01); A61L 29/085 (2013.01); A61L 29/145 (2013.01); A61L 29/16 (2013.01); A61L 33/064 (2013.01); A61L 33/08 (2013.01); A61L 2300/42 (2013.01);
Abstract

A thrombo-resistant catheter includes a hydrogel coating containing a thrombolytic agent. The thrombolytic agent may be a lyophilized tissue plasminogen activator. The catheter has an intraluminal surface and an extraluminal surface, and the hydrogel coating is disposed on the intraluminal surface and/or the extraluminal surface. The hydrogel coating may have a thickness in the range of about 50 nm to about 150 nm. The hydrogel coating may contain from about 0.1 wt. % to about 1 wt. % tissue plasminogen activator. The hydrogel coating may be made of a synthetic hydrogel or a natural hydrogel. Presently preferred synthetic hydrogels include polyacrylamide-based hydrogels. Presently preferred natural hydrogels include hyaluronic acid-based hydrogels. The hydrogel coating reacts in the presence of a physiological fluid to absorb water and elute the thrombolytic agent. The hydrogel controls elution of the thrombolytic agent. Examples of physiological fluid include interstitial fluid and blood.


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