The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2026
Filed:
Jan. 14, 2022
Exollence Co., Ltd., Seoul, KR;
Ewha University-industry Collaboration Foundation, Seoul, KR;
Ki Hwan Kwon, Seoul, KR;
Ji Hwa Chung, Gimpo-si, KR;
EXOLLENCE CO., LTD., Seoul, KR;
EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION, Seoul, KR;
Abstract
The present invention relates to an extracellular vesicle including a coronavirus-derived antigen protein or a gene encoding the protein, and a use of the extracellular vesicle. According to the present invention, when mice are immunized by administering an activated immune cell-derived extracellular vesicle loaded with an antigen protein or mRNA, excellent antigen-specific neutralizing antibody production and T cell response induction effects are confirmed. When the extracellular vesicle is stored under room-temperature and refrigerated conditions after freeze-drying, high stability and an excellent antibody production effect are experimentally confirmed. From these results, the extracellular vesicle according to the present invention or a vaccine composition including the same may serve as a platform applicable to various diseases with an excellent antigen-specific immune response induction effect and excellent stability, and thus is expected to be effectively used for the development of vaccines for preventing or treating various diseases including infectious diseases, particularly coronavirus infections.