The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2026
Filed:
Dec. 17, 2021
Genentech, Inc., South San Francisco, CA (US);
Michael F.T. Koehler, South San Francisco, CA (US);
Peter Andrew Smith, South San Francisco, CA (US);
Dana Winter, Montreal, CA;
Boubacar Sow, Montreal, CA;
Claudio Sturino, Montreal, CA;
Guillaume Pelletier, Saint-Lazare, CA;
Jonathan Boudreault, L'Ile-Perrot, CA;
Stéphanie Roy, Lachine, CA;
GENENTECH, INC., South San Francisco, CA (US);
Abstract
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidases SpsB and/or LepB, an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.