The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2026
Filed:
Sep. 17, 2021
Charité-universitätsmedizin Berlin, Berlin, DE;
Wolfgang Kübler, Berlin, DE;
Lasti Efrinanda Fuaadi, Berlin, DE;
Birgitt Gutbier, Berlin, DE;
Martin Witzenrath, Berlin, DE;
BOREALIS GMBH, Vienna, AT;
Abstract
The invention relates to a cystic fibrosis transmembrane conductance regulator (CFTR) modulator for use in the prevention and/or treatment of diseases involving endothelial and/or epithelial barrier dysfunctions. The disease does not comprise cystic fibrosis. The invention further relates to a pharmaceutical composition comprising a CFTR modulator as an active ingredient for use in the prevention and/or treatment of diseases involving endothelial and/or epithelial barrier dysfunctions. The invention further relates to a kit of parts for use in the prevention and/or treatment of diseases involving endothelial and/or epithelial barrier dysfunctions comprising i) a CFTR modulator and ii) a further CFTR modulator. The invention further relates to a method of treating a condition, disease or disorder involving endothelial and/or epithelial barrier dysfunctions in a subject, the method comprising administering a CFTR modulator to a subject, preferably a mammal, in the need thereof.