The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

Apr. 20, 2021
Applicants:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Francisco J. Schopfer, Pittsburgh, PA (US);

Bruce A. Freeman, Pittsburgh, PA (US);

Yang Zhao, Ann Arbor, MI (US);

Yuqing E. Chen, Superior Township, MI (US);

Jifeng Zhang, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/231 (2006.01); A61P 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/231 (2013.01); A61P 9/14 (2018.01);
Abstract

A method comprising administering to a subject having an aneurysm, suspected of having an aneurysm, or at risk of developing an aneurysm, a therapeutically effective amount of a compound selected from (i) a nitroalkene fatty acid, (ii) an unsaturated fatty acid having an electron withdrawing group, a leaving group, and a carbon-carbon double bond disposed between the electron withdrawing group and the leaving group, (iii) a thiolated nitro fatty acid, (iv) a dicarboxylic acid compound containing an electron withdrawing group, or a mixture of at least two of (i)-(iv).


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