The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2026

Filed:

Dec. 18, 2020
Applicant:

Georgia State University Research Foundation, Inc., Atlanta, GA (US);

Inventors:

Binghe Wang, Marietta, GA (US);

David W. Boykin, Atlanta, GA (US);

Arvind Kumar, Lilburn, GA (US);

Mengyuan Zhu, Cary, NC (US);

Manjusha Roy Choudhury, Atlanta, GA (US);

Bingchen Yu, Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 307/36 (2006.01); A61K 31/137 (2006.01); A61K 31/155 (2006.01); A61K 31/165 (2006.01); A61K 31/277 (2006.01); A61K 31/33 (2006.01); A61K 31/341 (2006.01); A61K 31/381 (2006.01); A61K 31/407 (2006.01); A61K 31/4178 (2006.01); A61K 31/4184 (2006.01); A61K 31/43 (2006.01); A61K 31/431 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/44 (2006.01); A61K 31/4709 (2006.01); A61K 31/496 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/5383 (2006.01); A61K 31/55 (2006.01); A61K 31/575 (2006.01); A61K 31/65 (2006.01); A61K 31/702 (2006.01); A61K 31/704 (2006.01); A61K 31/7048 (2006.01); A61K 31/7052 (2006.01); A61K 31/7056 (2006.01); A61K 38/12 (2006.01); A61P 31/04 (2006.01); C07C 219/28 (2006.01); C07C 257/18 (2006.01); C07C 279/18 (2006.01); C07C 323/45 (2006.01); C07D 213/30 (2006.01); C07D 233/20 (2006.01); C07D 233/22 (2006.01); C07D 235/18 (2006.01); C07D 239/06 (2006.01); C07D 307/52 (2006.01); C07D 307/54 (2006.01); C07D 307/68 (2006.01); C07D 333/20 (2006.01); C07D 333/22 (2006.01); C07D 345/00 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/155 (2013.01); A61K 31/137 (2013.01); A61K 31/165 (2013.01); A61K 31/277 (2013.01); A61K 31/33 (2013.01); A61K 31/341 (2013.01); A61K 31/381 (2013.01); A61K 31/407 (2013.01); A61K 31/4178 (2013.01); A61K 31/4184 (2013.01); A61K 31/43 (2013.01); A61K 31/431 (2013.01); A61K 31/437 (2013.01); A61K 31/4375 (2013.01); A61K 31/44 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/5383 (2013.01); A61K 31/55 (2013.01); A61K 31/575 (2013.01); A61K 31/65 (2013.01); A61K 31/702 (2013.01); A61K 31/704 (2013.01); A61K 31/7048 (2013.01); A61K 31/7052 (2013.01); A61K 31/7056 (2013.01); A61K 38/12 (2013.01); A61P 31/04 (2018.01); C07C 219/28 (2013.01); C07C 257/18 (2013.01); C07C 279/18 (2013.01); C07C 323/45 (2013.01); C07D 213/30 (2013.01); C07D 233/20 (2013.01); C07D 233/22 (2013.01); C07D 235/18 (2013.01); C07D 239/06 (2013.01); C07D 307/52 (2013.01); C07D 307/54 (2013.01); C07D 307/68 (2013.01); C07D 333/20 (2013.01); C07D 333/22 (2013.01); C07D 345/00 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01);
Abstract

Compounds and methods for use to treat a bacterial infection caused by, for example, gram positive bacteria, gram negative bacteria, and/or mycobacteria are provided herein. Also provided herein are compounds and methods for use in potentiating the effect of an antibiotic in the treatment of a bacterial infection. Pharmaceutical compositions including the compounds as described herein are also provided.


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