Dosimetry system for photodynamic anitmicrobial therapy device of infectious keratitis

Abstract

Systems and methods for an improved dosimeter for measuring dosage for photodynamic therapy treatment are provided. An example systems includes a dosimeter comprising a variable optical filter system configured to receive a second light, the second light comprising luminescence produced by singlet oxygen and one or more background signal and selectively transmit the luminescence and the one or more background signals as a third light, the variable optical filter system comprises a plurality of optical bandpass filters that are switchable to selectively transmit the luminescence and the one or more background signals. The dosimeter also includes a photoreceiver configured to receive the third light and configured to generate electrical output signals corresponding to the luminescence and the one or more background signals, the electrical output signals being indicative of an amount of the singlet oxygen produced based on activating the photosensitizer.