The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2026

Filed:

Feb. 09, 2024
Applicant:

Institute of Biophysics, Chinese Academy of Sciences, Beijing, CN;

Inventors:

Gang Ji, Beijing, CN;

Shuoguo Li, Beijing, CN;

Fei Sun, Beijing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6458 (2013.01);
Abstract

Disclosed are a real-time fluorescence monitoring cryo-focused ion beam processing device and a corresponding method. The device includes a vacuum chamber, an ion beam system, and a fluorescence imaging system. A cryo stage is provided in the vacuum chamber and is used for placing a frozen sample, in which a fluorescent marker is provided. The ion beam system is disposed on the vacuum chamber and directed to the frozen sample for ion beam processing the frozen sample. The fluorescence imaging system is arranged on the vacuum chamber and located below the frozen sample and is used for performing real-time optical imaging on the frozen sample. During processing, the fluorescence imaging system emits excitation light to the frozen sample to excite the fluorescent marker in the sample to emit fluorescence, which is received by the fluorescence imaging system to form an image of a target structure in the frozen sample.


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Ji, Gang. (2026). Real-time fluorescence monitoring system for cryo-focused ion beam milling device and method (U.S. Patent No. 12723984). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12723984

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