The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2026
Filed:
Oct. 26, 2021
Amgen Inc., Thousand Oaks, CA (US);
Brian Alan Lanman, Woodland Hills, CA (US);
Abhisek Banerjee, Bangalore, IN;
Margaret Chu-Moyer, Brookline, MA (US);
Dongcheng Dai, Corvallis, OR (US);
Matthew R. Kaller, Ventura, CA (US);
Patricia Lopez, Woodland Hills, CA (US);
Vu Van MA, Oak Park, CA (US);
Francesco Manoni, Newbury Park, CA (US);
Jose M. Medina, Thousand Oaks, CA (US);
Alexander J. Pickrell, Westlake Village, CA (US);
Nuria A. Tamayo, Newbury Park, CA (US);
Kai Zhu, Westlake Village, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present disclosure provides compounds of Formula (I) having activity as inhibitors of G12C mutant KRAS protein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses and methods of treating certain disorders, such as cancer, including but not limited to lung, pancreatic and colorectal cancers.