The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2026

Filed:

Apr. 11, 2025
Applicant:

Beijing Carrius Bio Ltd., Beijing, CN;

Inventor:

Ming Wang, Beijing, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 211/01 (2006.01); A61K 39/385 (2006.01); C07C 9/22 (2006.01); C07C 43/03 (2006.01); C07C 59/305 (2006.01); C07C 219/06 (2006.01); C07C 323/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07C 211/01 (2013.01); A61K 39/385 (2013.01); C07C 9/22 (2013.01); C07C 43/03 (2013.01); C07C 59/305 (2013.01); C07C 219/06 (2013.01); C07C 323/12 (2013.01); A61K 2039/53 (2013.01);
Abstract

The present invention provides an ionizable lipid compound, which can target spleen for delivery of biological macromolecules including nucleic acid drugs or nucleic acid vaccines with high efficiency. The present invention also relates to a lipid nanoparticle (LNP) comprising the ionizable lipid compound and an active molecule, and a pharmaceutical composition comprising the lipid nanoparticle.


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