The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2026
Filed:
Sep. 06, 2022
Eisai R&d Management Co., Ltd., Tokyo, JP;
Toshiyuki Tamai, Tokyo, JP;
Satoshi Nagao, Tokyo, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a pharmaceutical composition for treating a solid tumor, comprising (6S,9aS)—N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide (Compound A) represented by the formula (I) or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical composition is administered to a human subject together with an effective amount of a 5-HTreceptor antagonist to suppress gastrointestinal symptoms in such a manner that Compound A or the pharmaceutically acceptable salt thereof is administered twice daily at a dose of about 10 mg to about 150 mg per dose of Compound A; and the gastrointestinal symptom is a gastrointestinal symptom associated with administration of Compound A or a pharmaceutically acceptable salt thereof
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile