The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2026
Filed:
Sep. 15, 2021
Kyungpook National University Industry-academic Cooperation Foundation, Daegu, KR;
In-Kyu Lee, Daegu, KR;
Eun Jung Choi, Daegu, KR;
Chang Hyun Jeon, Daegu, KR;
Jae-Han Jeon, Daegu, KR;
Kyungpook National University Industry-Academic Cooperation Foundation, Buk-gu daegu, KR;
Abstract
The present invention relates to a pharmaceutical composition for preventing, treating, or ameliorating graft versus host disease (GVHD), comprising thiamine derivatives, in which the active ingredient of the pharmaceutical composition is fursultiamine, which can alleviate weight loss found in patients with GVHD, reduce the infiltration of liver and colon inflammatory cells, and effectively inhibit the production of allogeneic CD4+ IFNγ+ T cells, and thus can be effectively used for the prevention, treatment, or amelioration of GVHD.