The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Aug. 23, 2022
Applicant:

St. John's University, Queens, NY (US);

Inventors:

Michael Fagiola, Queens, NY (US);

Jerome Cantor, Queens, NY (US);

Assignee:

ST. JOHN'S UNIVERSITY, Queens, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 1/40 (2006.01); G01N 30/72 (2006.01); G01N 30/88 (2006.01); G01N 33/68 (2006.01); A61B 5/00 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6887 (2013.01); G01N 1/4077 (2013.01); G01N 30/7233 (2013.01); G01N 30/88 (2013.01); A61B 5/4848 (2013.01); G01N 2001/4083 (2013.01); G01N 2030/027 (2013.01); G01N 2030/8818 (2013.01); G01N 2333/78 (2013.01); G01N 2800/10 (2013.01); G01N 2800/122 (2013.01);
Abstract

The invention pertains to the use of a specific biomarker of elastin degradation (desmosine) that measures the extent and progression of chronic obstructive pulmonary disease (COPD). In addition to potentially serving as a screening procedure for COPD, it provides a real-time measure of COPD drug efficacy and may therefore supersede the use of less sensitive tests such as pulmonary function studies and computed tomography. Equally important, the current invention constitutes a marked improvement for measuring desmosine in tissues and body fluids by greatly shortening the time for detection of this molecule in liquid chromatography-tandem mass spectrometry (LC-MS-MS) assays that are the gold standard for such measurements. Unlike previous methods, the invention allows for the use of LC-MS-MS without modification, so the method can be applied to any laboratory that uses this equipment for other measurements. This would include forensic facilities that need to determine if undiagnosed COPD played a role in the loss of life.


Find Patent Forward Citations

Fagiola, Michael. (2026). Method for measuring copd biomarkers (U.S. Patent No. 12716898). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12716898

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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