The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

May. 09, 2023
Applicant:

Northwestern University, Evanston, IL (US);

Inventors:

Jonathan Rivnay, Evanston, IL (US);

Xudong Ji, Evanston, IL (US);

Assignee:

Northwestern University, Evanston, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/414 (2006.01); G01N 27/327 (2006.01); G01N 27/48 (2006.01);
U.S. Cl.
CPC ...
G01N 27/4145 (2013.01); G01N 27/3276 (2013.01); G01N 27/3277 (2013.01); G01N 27/48 (2013.01);
Abstract

Analyte sensing devices that include an electrochemical aptamer-based (E-AB) sensor integrated with an organic electrochemical transistor (OECT) for signal amplification are provided. The E-AB sensor has a three-electrode setup that includes an aptamer-functionalized working electrode, an independent reference electrode, and a counter electrode composed of a mixed ionic-electronic conductive polymer. In the sensors, the working electrode simultaneously serves as a gate electrode for an OECT, while the mixed ionic-electronic conductive polymer also acts as the transistor channel of the OECT. This integrated device design retains the features of both the E-AB sensor and the OECT, thereby enabling electrochemical measurements to be carried out by the E-AB sensor, while simultaneously monitoring changes in the in-plane conductivity of the OECT channel.


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