The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Apr. 07, 2023
Applicants:

Beijing Grand Johamu Pharmaceutical Company, Ltd., Beijing, CN;

Nanjing Gritpharmaco., Ltd., NanJing, CN;

Inventors:

Weiye Wei, Beijing, CN;

Jiannan Yang, Beijing, CN;

Xiaotao Wu, Beijing, CN;

Taotao Zhao, Beijing, CN;

Hao Wang, Beijing, CN;

Chao Li, Beijing, CN;

Lei Qu, Beijing, CN;

Bin Wang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); C07C 57/15 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 9/1617 (2013.01); A61K 9/1623 (2013.01); A61K 9/1652 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); C07C 57/15 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure provides a crystal form comprising a compound of Formula (I) and fumaric acid, wherein the crystal form satisfies at least one of the following conditions: (1) a particle size Dof the active pharmaceutical ingredient ranges from about 5 μm to about 60 μm; and (2) a particle size Dof the active pharmaceutical ingredient does not exceed about 30 μm; a pharmaceutical composition containing the crystal form, and a method for treating coronavirus-induced diseases by using the crystal form. The crystal form of the present disclosure enables the pharmaceutical composition containing the crystal form to have advantages such as a higher dissolution rate, a higher dissolution, and the like.


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