The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2026
Filed:
Apr. 29, 2021
President and Fellows of Harvard College, Cambridge, MA (US);
Memorial Sloan-kettering Cancer Center, New York, NY (US);
Christina M. Woo, Cambridge, MA (US);
David K. Miyamoto, Cambridge, MA (US);
Michael Kharas, New York, NY (US);
Sun Mi Park, New York, NY (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Memorial Sloan-Kettering Cancer Center, New York, NY (US);
Abstract
Provided herein are compounds that promote targeted degradation of IKZF2, a protein whose activity is implicated in the pathology of certain cancers (e.g., acute myeloid leukemia). Also provided are pharmaceutical compositions comprising the compounds. Also provided are methods of treating cancer, and methods of promoting the degradation of IKZF2 in a subject or biological sample by administering a compound or composition described herein.