The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Dec. 14, 2023
Applicant:

Intrabio Ltd., London, GB;

Inventor:
Assignee:

INTRABIO LTD., London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 235/12 (2006.01); A61K 31/223 (2006.01); A61P 25/00 (2006.01); C07C 233/47 (2006.01); C07C 233/52 (2006.01);
U.S. Cl.
CPC ...
C07C 235/12 (2013.01); A61K 31/223 (2013.01); A61P 25/00 (2018.01); C07C 233/47 (2013.01); C07C 233/52 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05);
Abstract

The present disclosure provides compounds represented by Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein R, R, and Rare as defined as set forth in the specification. The present disclosure also provides compounds having Formula I for use to treat or prevent the progression of a lysosomal storage disorder or a neurodegenerative disease in a subject, provide neuroprotection in a subject having a lysosomal storage disorder, treat or prevent a migraine, and the symptoms associated therewith, in a subject, or improve mobility and/or cognitive function in a subject.


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