The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Nov. 04, 2020
Applicant:

Northwestern University, Evanston, IL (US);

Inventors:

Maciej S. Lesniak, Evanston, IL (US);

Peng Zhang, Chicago, IL (US);

Assignee:

Northwestern University, Evanston, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 9/16 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 9/0019 (2013.01); A61K 9/0043 (2013.01); A61K 9/107 (2013.01); A61K 9/1617 (2013.01); A61K 9/1641 (2013.01); A61K 31/519 (2013.01); A61P 35/00 (2018.01);
Abstract

Disclosed are methods and compositions for treating cell proliferative diseases and disorders including cancers comprising tumor-associated myeloid cells (TAMCs) such as glioblastoma. The disclosed methods and composition may utilize or comprise cytotoxic lipid particles that comprise a surface-associated antibody or antigen-binding fragment thereof against PD-L1.


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