The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2026
Filed:
Jan. 06, 2021
Shanghai Huayu Biotechnology Co., Ltd., Shanghai, CN;
Fan Wu, Brookline, MA (US);
Zhanggui Wu, Brookline, WA (US);
SHANGHAI HUAYU BIOTECHNOLOGY CO. LTD, Shanghai, CN;
Abstract
Disclosed are methods for treating a cancer selected from breast cancer, colon cancer, ovarian cancer, or pancreatic cancer in a subject in need thereof, comprising administering a therapeutically effective amount of a compound of formula I or a pharmaceutically acceptable salt thereof, in combination with a poly (ADP)-ribose polymerase (PARP) inhibitor. The compound of formula I acts as a checkpoint kinase (CHK) inhibitor. The combination exhibits synergistic anti-tumor efficacy, including enhanced tumor cell growth inhibition at reduced effective concentrations. Also disclosed are pharmaceutically acceptable compositions comprising the compound of formula I and a PARP inhibitor.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile