The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Jun. 02, 2021
Applicants:

University of Florida Research Foundation, Inc., Gainesville, FL (US);

Amilyfe, Llc, Norwood, MA (US);

Inventors:

Sadasivan Vidyasagar, Gainesville, FL (US);

Astrid Grosche, Gainesville, FL (US);

Xiaodong Xu, Gainesville, FL (US);

Shanshan Lin, Gainesville, FL (US);

Stephen Gatto, Norwood, MA (US);

Robert Kenefick, Norwood, MA (US);

Samuel Cheuvront, Norwood, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 31/401 (2006.01); A61K 31/7004 (2006.01); A61K 31/7016 (2006.01); A61P 1/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/401 (2013.01); A61K 31/7004 (2013.01); A61K 31/7016 (2013.01); A61P 1/12 (2018.01);
Abstract

Amino acid formulations useful for treating diarrhea in a subject in need thereof are described herein. Such amino acid formulations and methods comprising administering same to a subject are useful for treating diarrhea, particularly diarrhea caused by or associated with bacterial infections wherein secretagogue-stimulated anion secretion from the intestinal crypt contributes to at least one symptom of diarrhea in the subject. Use of these amino acid formulations for the treatment of diarrhea in general or diarrhea associated with secretagogue-stimulated anion secretion from the intestinal crypt are encompassed herein, as are their use in the preparation of a medicament for the treatment of diarrhea in general or diarrhea associated with secretagogue-stimulated anion secretion from the intestinal crypt.


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