The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Mar. 25, 2021
Applicant:

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd, Jerusalem, IL;

Inventors:

Yechezkel Barenholz, Jerusalem, IL;

Ahuva Cern, Modiin, IL;

Amiram Goldblum, Tel Aviv, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 9/127 (2006.01); C07D 257/04 (2006.01); C07D 403/10 (2006.01);
U.S. Cl.
CPC ...
A61K 9/127 (2013.01); A61K 47/544 (2017.08); C07D 257/04 (2013.01); C07D 403/10 (2013.01);
Abstract

The present disclosure provides liposomal formulations comprising a lipid membrane comprising at least one liposome forming phospholipid and a sterol; and an intraliposomal aqueous compartment encapsulating at least one ATI receptor blocker (ARB) and a pH-dependent ionizable anion; with the liposomes having an effect upon administration to a subject in need of said effect, without causing a reduction in mean blood pressure of said subject of more than 50% as compared to the administration of the same amount of ARB in free form. The liposomes can be for systemic administration, e.g. by injection or for pulmonary administration, e.g. by inhalation.


Find Patent Forward Citations

Barenholz, Yechezkel. (2026). Liposomal formulations comprising at1 receptor blockers and uses thereof (U.S. Patent No. 12714669). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12714669

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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