The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Jul. 24, 2020
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Nathaniel Lynd, Austin, TX (US);

Aaron Burkey, Austin, TX (US);

Jacob Baltzegar, Columbia, SC (US);

Adrianne Rosales, Austin, TX (US);

Dale Harris, Austin, TX (US);

Alex Hillsley, Austin, TX (US);

Natalie Julia Czarnecki, Austin, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 1/125 (2025.01); C08G 81/02 (2006.01); C08L 71/02 (2006.01);
U.S. Cl.
CPC ...
A01N 1/125 (2025.01); C08G 81/025 (2013.01); C08L 71/02 (2013.01); C08G 2261/145 (2013.01);
Abstract

Disclosed herein are cryoprotective polymers. The cryoprotective polymers can include one or more DMSO-like moieties (e.g., one or more sulfoxide moieties, one or more sulfone moieties, or a combination thereof) that many the hydrogen-bonding characteristics of DMSO with the advantages of polymeric cryoprotectants. In doing so, very high post-thaw recovery of example cells and tissues can be achieved. The cryoprotective effects of these polymers can result from a limitation of total ice formation, a disruption of water hydrogen-bonding networks, and a well-timed vitrification of the unfrozen space between ice crystals. Also provided are cryoprotective solutions comprising these cryoprotective polymers as well as methods of using these polymers and solutions to preserve biological materials.


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