The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2026

Filed:

Feb. 22, 2021
Applicant:

Pioneer Hi-bred International, Inc., Johnston, IA (US);

Inventors:

Ajith Anand, Davis, CA (US);

Maren L Arling, Des Moines, IA (US);

Pierluigi Barone, Des Moines, IA (US);

Hyeon-Je Cho, Ankeny, IA (US);

William James Gordon-Kamm, Urbandale, IA (US);

Sandeep Kumar, Johnston, IA (US);

Brian Lenderts, Johnston, IA (US);

Keith S Lowe, Johnston, IA (US);

Sergei Svitashev, Johnston, IA (US);

Xinli Emily Wu, Johnston, IA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); A01H 6/46 (2018.01); A01H 6/54 (2018.01); C12N 9/22 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8213 (2013.01); A01H 6/4684 (2018.05); A01H 6/542 (2018.05); C12N 9/22 (2013.01); C12N 15/1031 (2013.01); C12N 15/8241 (2013.01); C12N 2510/00 (2013.01);
Abstract

Compositions and methods are provided for an inducible, high efficiency intra-genomic homologous recombination (IGHR) system in plants, that can be used for non-chimeric, heritable gene targeting. The advantage of IGHR approach to targeted integration is that every cell contains donor DNA and nuclease-encoding sequences, so that there are many potentially homology-directed targeting events that can occur during plant development.


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