The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2026

Filed:

Dec. 07, 2020
Applicants:

Shanghai Hansoh Biomedical Co., Ltd., Shanghai, CN;

Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Lianyungang, CN;

Inventors:

Hualing Xiao, Shanghai, CN;

Qiang Liu, Shanghai, CN;

Xingyun Lu, Shanghai, CN;

Jiaqiang Cai, Shanghai, CN;

Rudi Bao, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61K 31/519 (2006.01); A61P 11/00 (2006.01); A61P 13/00 (2006.01); A61P 15/00 (2006.01); A61P 25/00 (2006.01); C07D 487/04 (2006.01); C07D 487/14 (2006.01); C07D 498/14 (2006.01); C07D 513/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 498/14 (2013.01); C07D 513/14 (2013.01);
Abstract

Provided are a pyrazole-containing polycyclic derivative inhibitor, a preparation method therefor and an application thereof. In particular, provided are a compound as represented by formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and an application thereof as a P2X3 inhibitor in treatment of P2X3 receptor function disorders, particularly in treatment of neurogenic diseases, wherein the substituents in the formula (I) are the same as those in the description in definition.


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