The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2026

Filed:

Dec. 02, 2021
Applicant:

Allen Institute, Seattle, WA (US);

Inventors:

Constantinos Anastassiou, Seattle, WA (US);

Soo Yeun Lee, Seattle, WA (US);

Assignee:

Allen Institute, Seattle, WA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/36 (2006.01); A61N 1/05 (2006.01);
U.S. Cl.
CPC ...
A61N 1/36171 (2013.01); A61N 1/0531 (2013.01);
Abstract

Electrostimulating waveforms offering simultaneous and controllable cell-type-specific entrainment are described. The waveforms selectively entrain excitatory versus inhibitory cortical and hippocampal neurons including pyramidal neurons, parvalbumin neurons, and somatostatin neurons. The embodiment provides targeted electrical stimulation (ES) entrainment of excitatory versus inhibitory neurons. For example, the current disclosure provides methods of selectively entraining excitatory neurons with ES frequencies below 30 Hertz (Hz) and in particular embodiments to frequencies below 15 Hz, such as 8 Hz and 4 Hz. The current disclosure also provides methods of selectively entraining inhibitory neurons to ES frequencies of at least 30 Hz and depending on the type of inhibitory neuron, utilizing a frequency that is 30-60 Hz or a frequency that is greater than 100 Hz.


Find Patent Forward Citations

Anastassiou, Constantinos. (2026). Electrical stimulation entrainment of targeted neuronal cell types (U.S. Patent No. 12702841). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12702841

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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