The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2026
Filed:
Apr. 23, 2021
Applicants:
Taiho Pharmaceutical Co., Ltd., Tokyo, JP;
Astex Therapeutics Ltd., Cambridge, GB;
Inventors:
Assignees:
TAIHO PHARMACEUTICAL CO., LTD., Tokyo, JP;
ASTEX THERAPEUTICS LTD., Cambridge, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); A61K 31/166 (2006.01); A61K 31/416 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/5365 (2006.01); A61N 5/10 (2006.01); A61P 1/00 (2006.01); A61P 1/18 (2006.01); A61P 11/00 (2006.01); A61P 13/10 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4178 (2013.01); A61K 31/166 (2013.01); A61K 31/416 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5365 (2013.01); A61N 5/10 (2013.01); A61P 1/00 (2018.01); A61P 1/18 (2018.01); A61P 11/00 (2018.01); A61P 13/10 (2018.01); A61P 35/00 (2018.01);
Abstract
A method of treating cancer comprises administering: (a) a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof; and (b) a therapeutically effective amount of an additional anti-cancer agent, to a subject in need of such treatment, the compound of Formula (I) being: where X, R, R, ring A, L, L, L, and Rare as defined in this disclosure.