The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2026

Filed:

Nov. 10, 2022
Applicant:

Nantong University, Nantong, CN;

Inventors:

Xiaosong Gu, Nantong, CN;

Xiu Dai, Nantong, CN;

Xingzhong Gu, Nantong, CN;

Leilei Gong, Nantong, CN;

Meiyuan Li, Nantong, CN;

Hualin Sun, Nantong, CN;

Tianmei Qian, Nantong, CN;

Hongkui Wang, Nantong, CN;

Lai Xu, Nantong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 17/11 (2006.01); A61B 17/00 (2006.01); A61L 27/34 (2006.01); A61L 27/36 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
A61B 17/1128 (2013.01); A61L 27/34 (2013.01); A61L 27/3633 (2013.01); C12N 5/0669 (2013.01); A61B 2017/00526 (2013.01);
Abstract

A bionic nerve graft and a preparation method thereof is provided. The bionic nerve graft includes a helical stent, a nanofiber membrane, guide fibers and hBMSC-ECM. A surface of the helical stent is coated with the nanofiber membrane, the guide fibers and the hBMSC-ECM are placed in a tube cavity of the helical stent, and the raw materials of the helical stent, the nanofiber membrane and the guide fibers are all chitosan. The preparation method includes the following steps: preparing the helical stent by a mold pouring method, coating the surface of the helical stent with the nanofiber membrane by an electrostatic spinning method, preparing the guide fibers by a template method, and filling the guide fibers and the hBMSC-ECM in the helical stent with the surface coated with the nanofiber membrane.


Find Patent Forward Citations

Loading…