The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2026
Filed:
Feb. 11, 2022
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Jerusalem, IL;
Ludwig-maximilians-universität München, Munich, DE;
Eitan Lerner, Rehovot, IL;
Thorben Cordes, Gauting, DE;
Yair Razvag, Maon Avigail, IL;
Paz Drori, Nordia, IL;
Gabriel Moya, Munich, DE;
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEMLTD., Jerusalem, IL;
LUDWIG-MAXIMILIANS-UNIVERSITÄT, Munich, DE;
Abstract
Systems and methods that allow optical detection of nanoparticles according to size and interaction with specific antibodies. Using a biological sample combined with fluorescent dyes and fluorescently labeled antibodies, implementations of the disclosed system allow for detection of >100 particles having diameters as low as 100 nm in under 10 minutes. The detection mechanisms combine confocal detection of particles in microfluidic flow devices. Concentrating the sample using hydrodynamic focusing allows detection of particles having concentrations as low as 10particles per mL of the sample. These capabilities allow for the detection, identification, and quantitation of viruses from bodily fluids such as saliva, where biologically relevant virus concentrations of potentially infected subjects are within the range of 10-10particles/mL. The system and methods comprise a 'flow virometer' providing rapid, direct feedback regarding the existence of specific viruses in a biological sample and serves as a technological basis for commercial products.