The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2026

Filed:

Sep. 09, 2021
Applicant:

Tosoh Bioscience Llc, King of Prussia, PA (US);

Inventors:

Sébastien Rouzeau, Publier, FR;

David Thomas Gillespie, Pearland, TX (US);

Assignee:

TOSOH BIOSCIENCE LLC, King Of Prussia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/0205 (2024.01); G01N 15/14 (2006.01); G01N 21/51 (2006.01); G01N 21/47 (2006.01);
U.S. Cl.
CPC ...
G01N 15/0211 (2013.01); G01N 15/14 (2013.01); G01N 21/51 (2013.01); G01N 2015/1493 (2013.01); G01N 2021/4704 (2013.01);
Abstract

Methods for determining an assumption-free radius of gyration of particles in solution using a light scattering detector are disclosed. The method may include determining a first weighting factor based on a first form factor. The method may also include determining a second weighting factor based on a second form factor. The method may further include determining a first form factor contribution for the first form factor based on the first weighting factor and the second weighting factor. The method may also include determining a second form factor contribution for the second form factor based on the first weighting factor and the second weighting factor. The method may also include determining the assumption-free radius of gyration from the first and second form factor contributions.


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