The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2026

Filed:

Feb. 05, 2019
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Josue A. Goss, Rogers, AR (US);

Christophe Chantre, Cambridge, MA (US);

Luke A. Macqueen, Cambridge, MA (US);

Kevin Kit Parker, Cambridge, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/12 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); C12N 5/071 (2010.01); C12N 5/077 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12M 25/14 (2013.01); C12M 21/08 (2013.01); C12M 23/20 (2013.01); C12M 29/00 (2013.01); C12M 41/44 (2013.01); C12N 5/0652 (2013.01); C12N 5/0697 (2013.01); G01N 33/5088 (2013.01); C12N 2503/02 (2013.01);
Abstract

Systems and methods are provided including a housing configured to receive and engage a hollow tissue structure within a fluid chamber of the housing. A first pair of flow channels and a second pair of flow channels of the housing are fluidly coupled to the fluid chamber. The housing fluidly couples the first pair of flow channels and fluidly couples the second pair of flow channels via a second flow path such that a change in a fluid pressure differential between a first fluid in the first flow path and a second fluid in the second flow path deflects at least a portion of the hollow tissue structure causing a change in flow of the first fluid through the first pair of flow channels or a change in flow of the second fluid through the second pair of flow channels.


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