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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12698306 B1

PDFFull Text
Date of Patent:
Aug. 04, 2026

Filed:

Jan. 29, 2021

Bile acid-gcpii inhibitor conjugates to treat inflammatory diseases, including inflammatory bowel disease (ibd)

Applicants:

The Johns Hopkins University, Baltimore, MD (US);

Institute of Organic Chemistry & Biochemistry Av CR V.v.i., Prague, CZ;

Inventors:

Barbara Slusher, Baltimore, MD (US);

Diane E. Peters, Baltimore, MD (US);

Rana Rais, Baltimore, MD (US);

Pavel Majer, Prague, CZ;

Lukas Tenora, Prague, CZ;

Ivan Snajdr, Prague, CZ;

Assignees:

The Johns Hopkins University, Baltimore, MD (US);

Institute of Organic Chemistry & Biochemistry as CR V.V.I., Prague, CZ;

Attorneys:

Casimir Jones, SC

Jeffrey W. Childers

Primary Examiner:

Susanna Moore

Int. Cl.
CPC ...
C07J 51/00 (2006.01); A61P 29/00 (2006.01); C07J 33/00 (2006.01); C07J 41/00 (2006.01);
U.S. Cl.
CPC ...
C07J 51/00 (2013.01); A61P 29/00 (2018.01); C07J 33/002 (2013.01); C07J 41/0055 (2013.01);
Abstract

GCPII inhibitors comprising 2-(phosphonomethyl) pentanedioic acid (2-PMPA) conjugated to a bile acid and their use for treating a disease or condition associated with elevated levels of GCPII, including inflammatory bowel disease.

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Slusher, Barbara. (2026). Bile acid-gcpii inhibitor conjugates to treat inflammatory diseases, including inflammatory bowel disease (ibd) (U.S. Patent No. 12698306). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12698306

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