The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2026

Filed:

Oct. 24, 2023
Applicant:

Advancion Corporation, Buffalo Grove, IL (US);

Inventors:

Jordan Quinn, Long Grove, IL (US);

Shengwen Yuan, Northbrook, IL (US);

Assignee:

Advancion Corporation, Buffalo Grove, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/04 (2006.01);
U.S. Cl.
CPC ...
C07D 261/04 (2013.01);
Abstract

Disclosed herein are methods and processes of preparing 3-amino-(C)-alkan-1-ol, including optically active 3-amino-(C)-alkan-1-ol (e.g., optically active 3-amino-1-butanol such as (R)-3-amino-1-butanol). The 3-amino-(C)-alkan-1-ol may be optionally substituted at the 1-position, e.g., with OH, alkoxy, O-acetyl, or silyl groups, among others. The processes include contacting a 1-nitro-(C)-alkane with a vinyl source or an acetylene source in the presence of a base and a dehydrating agent to provide 3-(C)-alkyl-2-isoxazoline; and/or contacting the 3-(C)-alkyl-2-isoxazoline with hydrogen and a hydrogenation catalyst to provide 3-amino-(C)-alkan-1-ol.


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