The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2026

Filed:

Dec. 18, 2020
Applicant:

Beckman Coulter, Inc., Brea, CA (US);

Inventors:

Matthew S. Davis, Indianapolis, IN (US);

Kristina K. Lu, Indianapolis, IN (US);

Rachel Ellen Moschell, Carmel, IN (US);

Peter Robert Nei, Brownsburg, IN (US);

Mark F. Sauerburger, Zionsville, IN (US);

Zachary M. Smith, Avon, IN (US);

John S. Snider, Brownsburg, IN (US);

Jason L. Springston, Carmel, IN (US);

Assignee:

Beckman Coulter, Inc., Brea, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 7/00 (2006.01); B01L 9/06 (2006.01);
U.S. Cl.
CPC ...
B01L 7/54 (2013.01); B01L 9/06 (2013.01); B01L 2200/023 (2013.01); B01L 2200/147 (2013.01); B01L 2300/1822 (2013.01); B01L 2300/1894 (2013.01);
Abstract

A reaction vessel comprises a lower chamber with a first volume, and an upper chamber with a second volume greater than the first volume. A thermocycling system for heating the reaction vessel includes a lower heating zone to heat the lower chamber, an upper heating zone to heat the upper chamber, and a lid heater to heat an opening of the upper chamber. A method comprises loading a sample into a lower chamber of a reaction vessel, thermocycling the lower chamber using a lower heating zone of the thermo cycler, combining an additive into the sample to produce a combination filling the lower chamber and at least partially filling an upper chamber of the reaction vessel, and incubating the upper and lower chambers using the lower heating zone and an upper heating zone. The lower and upper chambers can have different wall thicknesses to facilitate heat transfer.


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